rhBDNF Lyophilized. PROTECT FROM MOISTURE. Recombinant, human brain drived neurotrophic factor expressed in E. coli. Promotes survival and growth of neurons. Structurally and functionally related to nerve growth factor. Its actions are mediated via the TrkB receptor. Biological activity: Supports survival of rat basal forebrain primary septal cultured neurons. Induces choline acetyltransferase (EC50 = 50 ng/ml). Purity: ≥97% by SDS-PAGE. Merck Index: 14, 6487
Ref.: Erickson, J.T., et al. 1996. J. Neurosci. 16, 5361. Leibrock, J., et al. 1989. Nature 341, 149. |
