Z-WE(OMe)HD(OMe)-FMK White solid. Supplied as a trifluoroacetate salt. PROTECT FROM MOISTURE. A potent, cell-permeable, and irreversible inhibitor of caspase-5. Strongly inhibits caspase-1. Also inhibits caspase-4 and caspase-8. Purity: single spot by TLC. Z-Trp-Glu(OMe)-His-Asp(OMe)-CH2F* Ref.: Garcia-Calvo, M., et al. 1998. J. Biol. Chem. 273, 32608. Thornberry, N.A., and Lazebnik, Y. 1998. Science 281, 1312. Rano, T., et al. 1997. Chem. Biol. 4, 149. |