Lyophilized. Recombinant, human caspases expressed in E. coli. Useful for the study of enzyme kinetics and regulation, for determining substrate specificity, for inhibitor screening, and as a positive control for caspase activity assays. Set includes 25 units of the following caspases: Caspase-1, Caspase-2, Caspase-3, Caspase-6, Caspase-7, Caspase-8, Caspase-9, and Caspase-10. Supplied with an informational insert. Ref.: Earnshaw, W.C., et al. 1999. Annu. Rev. Biochem. 68, 383. Stennicke, H.R. and Salvesen, G.S. 1999. Cell Death Differ. 6, 1054. Thornberry, N.A., and Lazebnik, Y. 1998. Science 281, 1312. Cohen, G. M. 1997. Biochem. J. 326, 1. Thornberry, N.A., et al. 1997. J. Biol. Chem. 272, 17907. |