7-[2-(2-Amino-4-thiazolyl)glyoxylamido]-3-(hydroxymethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate 72-(Z)-(O-methyloxime) Acetate, Na White crystalline solid. PROTECT FROM LIGHT. HYGROSCOPIC. Potent b-lactamase-resistant antibiotic of cephalosporin class. Active against Gram-positive and Gram-negative organisms, including Gram-negative anaerobes. Inhibits cell wall synthesis. Purity: ≥91% by HPLC (dry basis). Optical rotation: +58° to +64° (c = 1, H2O). pH (10%, H2O) 4.5 - 6.5. RTECS XI0250000, CAS 64485-93-4. Merck Index: 14, 1933
Ref.: Molinari, G., et al. 1991. J. Chemotherap. 3, 6. Vallee, F., and LeBel, M. 1991. Antimicrob. Agents Chemother. 35, 2057. |
