rhG-CSF Lyophilized. Carrier-free. Recombinant, human granulocyte colony-stimulating factor expressed in E. coli. A pleiotropic cytokine best known for its specific effects on proliferation, differentiation, and activation of hematopoietic cells of neutrophilic granulocyte lineage. Causes neutrophil sequestration in rabbit lungs. Biological activity: ED50 = 50-200 pg/ml as measured in a cell proliferation assay with the murine myeloblastic cell line NFS-60. Purity: ≥95% by SDS-PAGE. Contaminants: Endotoxin: ≤100 pg/µg G-CSF. RTECS VF1000000. Ref.: Inano, H., et al. 1998. Am. J. Respir. Cell. Mol. Biol. 19, 167. Nagata, S., and Fukunaga, R., 1991. Prog. Growth Factor Res. 3, 131. Nicola, N.A. 1989. Annu. Rev. Biochem. 58, 45. |
