rmG-CSF Lyophilized. Lyophilized from sterile-filtered PBS, 50 µg BSA/µg G-CSF. Recombinant, human granulocyte colony-stimulating factor expressed in E. coli. Pleiotropic cytokine best known for its specific effects on the proliferation, differentiation, and activation of hematopoietic cells of the neutrophilic granulocyte lineage. Induces binding of STAT1 and STAT3 to the IFN-g response region in human neutrophils. Biological activity: ED50 = 10-30 pg/ml as measured in a cell proliferation assay using a mouse myeloblastic cell line, NFS-60. Purity: >97% by SDS-PAGE. Contaminants: Endotoxin: 1 EU/µg G-CSF. Merck Index: 14, 4537
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