rhGM-CSF Lyophilized. Carrier-free. Recombinant, human granulocyte macrophage colony-stimulating factor expressed in E. coli. Pleiotropic cytokine that can stimulate the proliferation, maturation, and function of hematopoietic cells. Target cells include macrophages, granulocytes, and eosinophils. GM-CSF mediates host defense and inflammation and is associated with tumor growth and metastasis. Biological activity: ED50 = 20-100 pg/ml as measured in a cell proliferation assay with TF-1 cells. Purity: ≥ 95% by SDS-PAGE. Contaminants: Endotoxin: ≤ 0.1 ng/µg GM-CSF.. Merck Index: 14, 4538
Ref.: Tsuruta, N., et al. 1998. Cancer 82, 2173. Moore, M.A. 1991. Annu. Rev. Immunol. 9, 159. |
