rmM-CSF Lyophilized. Lyophilized from sterile-filtered PBS, 50 µg BSA/µg M-CSF. Recombinant, mouse macrophage colony-stimulating factor expressed in E. coli. Stimulates the formation of macrophage colonies from bone marrow hematopoietic progenitor cells. Induces cell death in HIV-1 infected monocytes. Biological activity: ED50 = 0.5-1.5 ng/ml as measured in a cell proliferation assay using the M-CSF-dependent mouse monocytic cell line, M-NFS-60. Purity: ≥97% by SDS-PAGE. Contaminants: Endotoxin: ≤1 EU/ug M-CSF.. RTECS GI5500000. Ref.: Bergamini, A., et al. 1994. Immunol. Lett. 42, 35. Hattersley, G., et al. 1991. Biochem. Biophys. Res. Commun. 177, 526. Ladner, M.B., et al. 1988. Proc. Natl. Acad. Sci. USA 85, 6706. |
