v-erb-a erythroblastic leukemia viral oncogene homolog 4 Liquid. In 100 mM NaCl, 50 mM Tris-HCl, 15 mM reduced glutathione, 5 mM DTT, 20% glycerol, pH 8.0. AVOID FREEZE/THAW CYCLES. Recombinant, human ErbB4 fused at the N-terminus to a GST-His6thrombin cleavage site sequence and expressed in S. frugiperda insect cells using a baculovirus expression system. ErbB4 is a member of the epidermal growth factor (EGF) family and the ErbB family of receptor tyrosine kinases. It mediates responses to EGF-like growth factors and plays an important role in cardiovascular and neural development and differentiation of the mammary gland. Specific activity: ≥20 U/µg protein. One unit is defined as the amount of enzyme that will transfer 1 nmol phosphate to Poly(Ala, Glu, Lys, Tyr)6:2:5:1 per min at 30°C, using variable concentrations of ATP (100-988 nM). Ref.: Maata, J., et al. 2006. Mol. Biol. Cell 17, 67. Amin, D.N., et al. 2004. Oncogene 23, 1428. Junttila, T.T., et al. 2000 Trend. Cardiovasc. Med. 10, 304. |
