Fibroblast Growth Factor Receptor 1
Flt-2 Liquid. In 100 mM NaCl, 50 mM Tris-HCl, 5 mM DTT, 4 mM reduced glutathione, 20% glycerol, pH 8.0. AVOID FREEZE/THAW CYCLES. Recombinant, human FGFR1 fused at the N-terminus to a GST-His6-thrombin cleavage site sequence and expressed in S. frugiperda insect cells. FGFR1 is a receptor tyrosine kinase that is involved in important processes such as cell division, regulation of cell growth and maturation, formation of blood vessels, wound healing, and embryonic development. Specific activity: ≥15 U/mg protein. One unit is defined as the amount of enzyme that will transfer 1 nmol phosphate to Poly(Glu,Tyr)4:1 per min at 30°C, using variable concentrations from 0.1 µM to 8.42 µM ATP. Ref.: Dvorak, P., et. al. 2005. Stem Cells 23, 1200. Antoine, M., et al. 2005. Growth Factors 23, 87. Johnson, D.E. and Williams, L.T. 1993. Adv. Cancer Res. 60, 1. |
