c-Jun N-terminal kinase 3
Jun kinase
MAPK10
Mitogen-activated protein kinase 10
Rat stress-activated protein kinase b Liquid. In 100 mM NaCl, 50 mM Tris-HCl, 5 mM DTT, 15 mM reduced glutathione, 20% glycerol, pH 8.0. AVOID FREEZE/THAW CYCLES. Recombinant, human JNK3 fused at the N-terminus to a GST-His6-thrombin cleavage site tag and expressed in S. frugiperda insect cells using a baculovirus expression system. JNK3 belongs to the MAP kinase family and is found in abundance in the hippocampus and neocortex areas of the brain. It plays a critical role in activation of c-Jun and apoptosis. Specific activity: ≥0.1 U/mg protein. One unit is defined as the amount of enzyme required to transfer 1 nmol phosphate to Rb-CTF per min at 30 °C using variable concentrations of ATP (0.1-0.312 µM). Ref.: Bruckner, S.R., et al. 2001. J. Neurochem. 78, 298. |
