CSF-1 Receptor Inhibitor IV
5-Cyano-N-(2,5-di(piperidin-1-yl)phenyl)furan-2-carboxamide Yellow solid. PROTECT FROM LIGHT. PACKAGED UNDER INERT GAS. A cell-permeable furan carboxamide compound that acts as a potent, reversible, and ATP-competitive cFMS/CSF-1R inhibitor that blocks cFMS autophosphorylation both in CSF-1/M-CSF-stimulated HEK-293 cells (IC50 = 76 nM) and in cell-free in vitro kinase assays (IC50 = 17 nM). Purity: ≥95% by HPLC. Ref.: Patch, R.J., et al. 2007. Bioorg. Med. Chem. Lett. 17, 6070. | 
