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  aA-Interferon, Human, Recombinant, E. coli
Cat. No. 407294  
All Categories » Calbiochem » Proteins and Enzymes » Chemokines and Cytokines » Cytokines » Interferons

rhIFN-aA

Liquid. In PBS containing 0.1% BSA. AVOID FREEZE/THAW CYCLES. Recombinant, human aA-interferon expressed in E. coli. Antiviral, anti-neoplastic agent. aA-Interferon exhibits therapeutic potential with chronic viral hepatitis, polycythemia vera, and various malignancies. It enhances natural killer cell activity, suppresses bone marrow function, and induces apoptotic cell death in non-melanoma skin cancer. NOTE: 1MU = 1,000,000 units. Activity: ≥5 x 106 units/ml. Specific activity: ≥2.8 x 108 units/mg protein. One unit of interferon per ml of medium will cause a 50% inhibition of VSV-induced cytopathic effect on bovine MDBK cells. Units are determined with respect to the NIH international reference standard for human aA-IFN. Dilute in aqueous buffer containing at least 0.1% BSA or HSA. Purity: ≥95% by SDS-PAGE. Note: 1 MU = 1,000,000 units.

Merck Index: 14, 4990
Ref.: Fujishima, H., et al. 1998. Int. J. Cancer 76, 423. Haria, M., and Benfield, P. 1995. Drugs 50, 873. Familletti, P.C., et al. 1981. Methods Enzymol. 78, 387.

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5 MUY$180.00

SolubilityMolecular FormulaMol. Wt.
  19241 

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407294: aA-Interferon, Human, Recombinant, E. coli - English
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Related Categories:
All Categories » Calbiochem » Proteins and Enzymes » Chemokines and Cytokines » Cytokines » Interferons

Selected Citations:
  1. Sambit K. Nanda and Michael D. Baron. (2006) Rinderpest virus blocks type I and type II interferon action: role of structural and nonstructural proteins. Journal of Virology 80, 7555-7568.
  2. Phuong Thi Nguyen Sarkis, et al. (2006) STAT1-independent cell type-specific regulation of antiviral APOBEC3G by IFN-α. Journal of Immunology 177, 4530-4540.