IFN-g
Interferon g precursor
rmIFN-g Lyophilized. Lyophilized from 0.5X PBS, pH 7.2. PROTECT FROM MOISTURE. Recombinant, mouse g-interferon (g-IFN) expressed in E. coli as a single, non-glycosylated polypeptide containing 134 amino acids. Purified by chromatographic methods. IFN-g is a type II cytokine produced by activated T cells and natural killer cells. It plays a significant role immunoregulation and has been implicated in the induction of the expression of class II histocompatibility molecules in cells that do not normally express them, resulting in autoimmune disease. Biological activity: Reported as IU/mg on a lot-specific basis using a cytopathic effect inhibition assay.. Purity: ≥95% by RP-HPLC, FPLC, and SDS-PAGE. Contaminants: Endotoxins: ≤1 EU/µg IFN-g. Ref.: Alvarado, J., et al. 2005. Immunol. Lett. 99, 109. Di Rosa, M., et al. 2005. Clin. Chem. Lab. Med. 43, 499. Malaguarnera, L., et al. 2005. J. Clin. Lab. Anal. 19, 128. |
