Anti-MAP Kinase Kinase

Host: Rabbit

Isotype: IgG

Immunogen: a synthetic peptide (MPKKKPTPIQLNC) corresponding to amino acids 1-12 of rat MEK1, conjugated to KLH

Form: Liquid

Formulation: In PBS, 50% glycerol, pH 7.2.

Preservative: ≤0.1% sodium azide

Positive Control: Human thymus (HTB163, Hs67), fibroblast (A431), HeLa cell, mouse fibroblasts (3T3), rat brain, muscle, spleen, testis, mouse brain, spleen, testis, or Xenopus ovary tissue

Comments: Recognizes the ~43 kDa MEK1 protein in human thymus and A431 and HeLa cells.

Ref.: Xu, L., et al. 1997. Genes Dev. 11, 106. Riches, D.W., et al. 1996. Immunobiology 195, 477. Hardie, G., and Hanks, S. 1995. in The Protein Kinase Facts Book, Protein-Serine Kinases p. 418, Academic Press, San Diego, CA. Xia, Z., et al. 1995. Science 270, 1326. Zheng, C.F., and Guan, K.L. 1993. J. Biol. Chem. 268, 11435. Huang, W., et al. 1993. Proc. Natl. Acad. Sci USA 90, 10947. Wu, J., et al. 1993. Proc. Natl. Acad. Sci. USA 90, 173.