3-(1-Methylpiperidinium)-1-propane Sulfonate White solid. HYGROSCOPIC. A non-detergent sulfobetaine useful for the renaturation of unfolded proteins. At 1.8 M, NDSB-221 yields about 35% in native hen egg white lysozyme (HEWL), which is about 10-fold higher than in the absence of NDSB-221. At about 1.5 M, NDSB-221 efficiently increases the renaturation of b-D-galactosidase. Purity: ≥95% by TLC. Ref.: Goldberg, M.E., et al. 1996. Folding & Design 1, 21. R: 36/37/38; S: 26-36 |