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| | Anti-P-Glycoprotein Mouse mAb (C494) |
|  | Cat. No. 517312 |
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| Host: Mouse | | Isotype: IgG2a | | Immunogen: SDS-solubilized plasma membranes of a multidrug resistant (MDR) Chinese hamster ovary (CHO) cell line and a human leukemic cell line | | Epitope: gene-specific internal cellular epitope present only on the MDR1 isoform of P-glycoprotein | | Form: Liquid | | Formulation: In PBS, 1% BSA. | | Preservative: ≤0.1% sodium azide | | Positive Control: Cell lines or frozen tissue, such as human liver or colon. | | Comments: Recognizes the ~170 kDa MDR1 isoform of P-glycoprotein. Does not cross-react with the MDR3 P-glycoprotein. | | Ref.: Rao, V.V., et al. 1994. Cancer Res. 54, 1536. Toth, K., et al. 1992. Am. J. Pathol. 140, 1009. Georges, E., et al. 1990. Proc. Natl. Acad. Sci. USA 87, 152. |
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| C494 | hamster, human | FC, FS, IB, IC, IP, PS
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