cAMP-specific phosphodiesterase 4A isoform 4 PDE4A4 Liquid. In 150 mM NaCl, 10 mM Tris-HCl, pH 8.3. AVOID FREEZE/THAW CYCLES. Full-length, recombinant, human phosphodiesterase 4A4 expressed in S. frugiperda insect cells using a baculovirus expression system. Supplied as a partially purified, catalytically active preparation. Activity: ≥0.5 units/µl. One unit is defined as the amount of enzyme that will convert 1 pmole cAMP to AMP per min at 30°C, pH 7.5. Ref.: Gibson, L.C.D., et al. 2006. Eur. J. Pharmacol. 538, 39. Xu, R.X., et al. 2000. Science 288, 1822. |