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  Phosphodiesterase 11A1, Active, Human, Recombinant, S. frugiperda
Cat. No. 524735  
All Categories » Calbiochem » Proteins and Enzymes » Phosphodiesterases

cAMP/cGMP cyclic nucleotide phosphodiesterase 11A1
PDE11A1

Liquid. In 150 mM NaCl, 10 mM Tris, 0.1% NP-40, pH 8.3. Full-length, recombinant, human phosphodiesterase 11A1 expressed in S frugiperda insect cells using a baculovirus expression system. Supplied as a partially purified preparation. Activity: ≥0.5 units/µl. One unit is defined as the amount of enzyme that will convert 1 pmole cAMP to AMP per min at pH 7.5, 30°C.

Ref.: Gibson, L.C.D., et al. 2006. Eur. J. Pharmacol. 538, 39. Hetman, J.M., et al. 2000 Proc. Natl. Acad. Sci. USA 97, 12891.

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Phosphodiesterase 11A1 was treated with increasing concentration of the inhibitor, Dipyridamole, and the activity assayed. the IC50 for this inhibition is 830 nM.

Related Literature:

Biologics 32.2

Material Safety Data Sheets:
524735: Phosphodiesterase 11A1, Active, Human, Recombinant, S. frugiperda - English
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All Categories » Calbiochem » Proteins and Enzymes » Phosphodiesterases