Purple solid. PROTECT FROM LIGHT. PACKAGED UNDER INERT GAS. The racemic mixture of a pyridocarbazolo-cyclopentadienyl Ruthenium complex that acts as a ATP-binding site-targeting, reversible, and highly potent inhibitor of PIM-1 (IC50 = 0.5 and 3 nM for the (S)- and (R)-enantiomer, respectively) with ∼10-fold selectivity over GSK-3a (IC50 = 15 and 20 nM for the (S)- and (R)-enantiomer, respectively). Purity: ≥95% by HPLC. Ref.: Bergman, H. and Meggers, E., 2006. Org. Lett. 8, 5465.
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