5-(5,6-Dimethoxybenzimidazol-1-yl)-3-(4-methanesulfonyl-benzyloxy)-thiophene-2-carboxamide
Polo-like Kinase Inhibitor I Tan solid. PROTECT FROM LIGHT. PACKAGED UNDER INERT GAS. A thiophenecarboxamide compound that acts as a potent and ATP-binding site-targeting inhibitor of polo-like kinase 1 (IC50 = 126 nM) with excellent selectivity over IKK-2 and IKK-3 (IC50 > 16 µM). Purity: ≥98% by HPLC. Ref.: Bamborough, P., et al. 2006. Bioorg. Med. Chem. Lett. 16, 6236. | 
