Rab Escort Protein Liquid. In 25 mM HEPES, 25 mM NaCl, 5 mM DTT, pH 7.2. AVOID FREEZE/THAW CYCLES. Recombinant, rat REP-1 fused to a His•Tag® sequence and expressed in S. frugiperda insect cells. A molecular chaperone that binds to Rab proteins stoichiometrically and promotes GGTase-II (Cat. No. 345855) catalytic activity. Purity: ≥90% by SDS-PAGE. Ref.: Alexandrov, K., et al. 1999. Eur. J. Biochem. 265, 160. Alexandrov, K., et al. 1998. FEBS Lett. 425, 460. Casey, P.J. and Seabra, M.C. 1996. J. Biol. Chem. 271, 5289. Armstrong, S.A., et al. 1995. Methods Enzymol. 257, 30. |
